Iron Toxicity Post #22: There is a difference between ‘Iron Deficiency and ‘Iron Dysregulation’!

Posted on March 4, 2016 by Morley Robbins

Calling all those lost in iatrogenic-induced iron anemia.

Please take note of this critical study:

Matak, P., et al. (2013). “Copper deficiency leads to anemia, duodenal hypoxia, upregulation of HIF-2a and altered expression of iron absorption genes in mice.”

Now, granted, this is not the easiest article to read, but it puts the spotlight on the truth.

Iron metabolism is ruled and regulated by copper status; not iron status and certainly not ferritin status!

As I’ve stated ad nauseum, there is a huge difference between “Iron deficiency” (very rare) and “Iron dysregulation” (very common). It’s time we all learn this fact about iron and copper metabolism. 

I would like to ask the following:

1. Please take a moment to review the abstract, the introduction and the conclusion.  This should rattle your cage about the profound relationship between copper <> iron. This is not a user-friendly article, but the pearls abound in this study.

2. Insist that your favorite practitioner read this study from stem to stern. (I would suggest you ask for a summary of their understanding.)

3) Insist that you get the full Monty Iron Panel — that focuses on copper.  Learn the truth of your likely iron dysregulation issue.

4) Based on the above, I’d recommend you re-think your supplement and medication regime.

5) And finally, based on the results, you might want to pursue increasing your Cp (ceruloplasmin) with a vengeance.

Hope you all find this instructive, helpful & healthful.

A votre sante!

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