“The two most Important Days of your Life: the day you were born, and the day you discover why!” — Mark Twain
I love that quote from Mr Clemmons! He was such a sage. You know he is right; the day you finally figure out why you’re here is magical. It is indelibly etched in my psyche and relates entirely to stepping onto this virtual podium or some would say, bully pulpit! Nevertheless, I’m having the time of my life and I never regret this 2nd birthday.
Yesterday there was a thread on hypothyroidism that had some very interesting comments and links, not the least of which was this one on red light!
I also enjoyed the appearance of our light being Jack Kruse, MD. He never fails to stimulate our little grey cells. In any event, I elected to take the dive with the blog on how red light helps to address an underactive thyroid. It was provocative and thoughtful, but do people have any idea where red light comes from inside of our cells?
Red light is generated when there is proper function of cytochrome c oxidase (Complex IV) of the mitochondrial electron transport chain (ETC). Why is that?
Complex IV does not work without bioavailable copper. It is also worth noting that copper and red light have a very symbiotic relationship.
So this blog article is an important clue about what is missing from a healthy thyroid is bioavailable copper. Where is that copper absence greatest? The key enzyme thyroid peroxidase (TPO) works best when there is wholefood vitamin C in the system. Whole food vitamin C is a source of bioavailable copper with tyrosinase at the core. Tyrosinase has a connection to the tyrosines that are being loaded with iodine. I am surprised that I seem to be the only one that sees this obvious deflection of reality by the world of convention obsessed with taking our thyroids hostage.
In any event, that got me thinking and searching this morning for some additional research re this red light phenomenon. What I came across is an absolute blockbuster:
Kim, H.P. (2014). “Lightening up Light Therapy: Activation of Retrograde Pathway by Photobiomodulation”
I know you all have very active, demanding and stress-filled lives. But please, take the 30 min it will take you to read through this very important and timely study.
What’s important to understand at the outset that Photobiomodulation (PBM) is considered a cutting edge mechanism for addressing metabolic shortages and dysfunction via the use of low level laser therapy (LLLT).
Yes, there’s great buzz about using lasers, LEDs, and related technology. It clearly works to relieve symptoms, but is it just another expensive crutch or just more diversion from the real mineral and metabolic issues? I would question whether fundamentally, does PBM correct the underlying issues that are causing this metabolic chaos?
I could spend the rest of this month commenting on what I learned reading this critical article, but what i want to stress are just a few key points:
- Rapidly growing cells prefer cell death instead of fixing the damaged mitochondria
- Electromagnetic light must ionize biological systems that it effects
- Irradiation [by] external electromagnetic energy can increase and substitute [emphasis added] for endogenous ATP production
- Radiation of red light (at 628 nm on the Light Spectrum) results in expression shifts of 111 genes in Hs27 human fibroblasts (Zhang, 2003). I would encourage you to read that sentence again!
Zhang, Z., Song, S., et al. (2003). “cDNA MicroarrayAnalysis of Gene Expression Pro¢les in Human Fibroblast Cells Irradiated with Red Light.”
- These 111 expressive shifts were grouped into 10 functional categories that promoted extracellular matrix proteins, orchestrated an increase in adenosine triphosphate (ATP) production, and also orchestrated an increase in cellular stress resistance [again, emphasis added]. That is the granddaddy of them all.
- Retrograde signaling [a form of mitochondrial stress response] can be mediated [another way of saying stimulated] by:
- Mitochondrial membrane potential (caused by copper<>iron dysregulation)
- Reactive oxygen species (ROS) (caused by copper<>iron dysregulation)
- Changes in calcium flow (caused by iron dysregulation affecting magnesium status)
- Nitric oxide binding to cytochrome c oxidase, again, caused by iron dysregulation which is spelled out here:
Cornejo, P. et al. “Chronic iron overload inducible nitric oxide synthase expression in rat liver.”
To those wishing to dig in even deeper, please follow this trail. These are both blockbuster articles, as well:
Lane, N. (2006). “Power Games.”
Karu, T.I. (2008). “Mitochondrial Signaling in Mammalian Cells Activated by Red & Near-IR Radiation”
Do you follow my point? There is clearly mitochondrial stress and what we are now learning is that it reaches over and touches the nucleus. (Please see the Fig. 1 below)
Think this iron-induced oxidative stress, as noted in points 6a thru 6d might just be the true source of the genetic defects that we’re supposed to believe come from mars?
These exogenous electromagnetic machines emit a red light that clearly helps to correct this chaos and confusion inside our cells. So, why am I not excited at this prospect?
You were not born with a red light deficiency. You were born with excess, unbound iron along with a notable shortage of bioavailable copper. I believe that is a fact in the research.
I know that these powerful and penetrating research studies are lighting the way for what the true issues are; just as we’ve been saying for four years.
Please don’t misunderstand my comments above; I am very excited with these developments. In fact, I’m seriously contemplating adding red light to the Root Cause Protocol. It’s that powerful, but I do so as a means to an end (crutch). The ultimate purpose in our efforts on Magnesium Advocacy Group (MAG) is to create more ceruloplasmin and allow the body to regain its mineral and metabolic homeostasis.
I was also fascinated to learn that the great Otto Warburg knew much of this back in 1931 when he received the Nobel Prize for his work on none other than the mitochondrial respiratory enzyme that was related to hemoglobin, which turns out to be cytochrome c oxidase.
We have learned a thing or two since 1931, but he was on the trail. Here is what Otto Warburg had to say about his Nobel speech award at the banquet in December of 1931:
Warburg, O. (1931). “The Oxygen-Transferring Ferment of Respiration.”
Dr Warburg is credited with theorizing the cause of cancer. It turns out that that is not entirely correct.
Here’s a provocative overview of what he did discover:
“What Otto Warburg actually discovered about cancer”
What Dr Warburg did know was that cancer cells had three key conditions:
1) Low pH 2) Low oxygen and 3) Low ATP.
Intriguing! That means when oxygen is low, the cell is forced to produce ATP via fermentation, and not via oxygen, which is its preferred route.
It turns out that Otto Warburg was studying the key mitochondrial enzyme (Cytochrome c Oxidase) that is fuelled by bioavailable Copper and he theorized the very three cellular conditions that are caused by excess, unbound iron.
Absolutely fascinating! Forgive me, but my mind’s blown at this point!
Now here’s what you may not know:
When the mitochondria have access to oxygen to “burn its food-based fuel,” it is relying on copper to oxidize the sugars and fats to enable the production of ATP.
Here is the breakdown:
- 1 Unit of fat yields 120 ATPs
- 1 Unit of sugar yields 32-34 ATPs
- When the cell is forced to go anaerobic (because of a loss of copper and/or excess of iron) and fermentation is used to breakdown the sugars, the yield is 2 ATPs (Please note the prevalence of magnesium (Mg) ions needed to make the anaerobic citric acid cycle work properly)
The methodical depletion of copper in our diet over the last 100yrs, and the known process of iron fortification that have introduced absurd levels of iron into our bodies have lowered our ability to use “gas” that can do 120 MPG or 32 MPG. We are forced to ferment our foods and burn up whatever magnesium we might possibly have. For those of you wondering how and why you have chronic fatigue please look no further.
Just know that we are on the right track with our focus on MAG and for those that are just joining us, please take the time to familiarize yourself with the Video and the Root Cause Protocol.
Taking the time to do that just might save your life, and it will certainly save you years of misery groping for a solution in a conventional medical system that is only committed to treating your condition. The latest gadget in their arsenal of goodies is their laser that helps, but only treats your condition.
MAG is fully committed to allowing you to regain your mineral and metabolic balance – naturally.
A votre sante!
Morley M Robbins
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