This post is based on a tale of two irons, hepcidin peptide that regulates them and causes chaos, confusion, clinical conditions and clinical currency.
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Excess iron causes calcification all over the body, including the soft tissues and organs. We’re talking arterial plaque, cataracts, liver and gallbladder stones, etc.
Textbook by world-renowned hematologists gives us one sentence about the cause of iron overload and its impact on a litany of diseases. Absence of ceruloplasmin in the neurons and retina results in lipid peroxidation that in turn causes cell damage and death, followed by organ dysfunction.