Tag: ferroxidase
Iron Toxicity Post #76: ‘Hypoferremia’ (Low Serum Iron) occurs in ANY Inflammatory state
Hypoferremia occurs in any inflamed state and it is code for low bioavailable copper not lack of iron.
Read MoreIron Toxicity Post #75: PROOF that Copper Deficiency is the CAUSE of so-called ‘anemia’
How does iron get out of enterocytes? What causes buildup of iron in the tissues all over the body?
Read MoreIron Toxicity Post #71: There is no iron deficiency anemia on planet earth, but there is a pandemic of anemia adiponectin deficiency
There is no “Anemia” on Planet Earth, but there is a pandemic of anemia! adiponectin deficiency, a key and little discussed hormone whose dysfunctions are the gateway to insulin resistance, atherosclerosis, diabetes, hypertension, dyslipidemia, fatty acid dysregulation, PCOS, weight gain/obesity, increased inflammation, as well as increased oxidative stress.
Read MoreIron Toxicity Post #66: ‘Iron and the RBC (Red Blood Cell): Is this where the assault begin?
Iron and the RBC (Red Blood Cells): Is this where the oxidative assault begins? [Hint: yes!]
Read MoreIron Toxicity Post #65: There is NO such thing as ‘Iron Metabolism’. There is ONLY Copper<>Iron Metabolism
This iron post has nine articles that examine iron metabolism and homeostasis. But nowhere do they highlight that there is no such thing as ‘Iron Metabolism’. There is only Copper<>Iron Metabolism, and Iron is the dummy!
Read MoreIron Toxicity Post #64: Ferroxidase blocks the Hydroxyl Radical (OH*)
Ferroxidase blocks the hydroxyl radical (OH*).
Read MoreIron Toxicity Post #59: A Tale of two irons and the hepcidin peptide that regulates them
This post is based on a tale of two irons, hepcidin peptide that regulates them and causes chaos, confusion, clinical conditions and clinical currency.
Read MoreIron Toxicity Post #58: Toto is my HERO!
Excess iron causes calcification all over the body, including the soft tissues and organs. We're talking arterial plaque, cataracts, liver and gallbladder stones, etc.
Read MoreIron Toxicity Post #57: The very source of this Iron-c crisis that is pandemic on this planet
Textbook by world-renowned hematologists gives us one sentence about the cause of iron overload and its impact on a litany of diseases. Absence of ceruloplasmin in the neurons and retina results in lipid peroxidation that in turn causes cell damage and death, followed by organ dysfunction.
Read MoreIron Toxicity Post #55: Ferritin is NOTHING, Hemosiderin is EVERYTHING!
Ferritin in the serum is a sign of tissue pathophysiology. Without the ceruloplasmin ferroxidase enzyme, iron doesn't load properly into ferritin. So it gets damaged and takes on the properties of hemosiderin where iron is stored and doesn't come out.
Read MoreIron Toxicity Post #52
Your iron isn’t low, it’s non-functional: Make it functional by raising ceruloplasmin.
Read MoreIron Toxicity Post #51: The Deceit of ‘Anemia’
You are not anemic! You have ‘anemia’ of chronic inflammation, which means you are iron toxic, and it's being stored in your tissues.
Read MoreIron Toxicity Post #47: The truth about the cause of mitochondrial dysfunction (as least as I see it)
How the key (copper) and the fuel (cardiolipin) prevents mitochondrial dysfunction in the lipids getting rusty. The cause of mitochondrial dysfunction.
Read MoreIron Toxicity Post #39: excess unbound iron is very bad! Get properly tested.
Low hemoglobin, ferritin, serum iron and saturation are all indications of iron dysregulation caused by low bioavailable copper which is expressed as low ceruloplasmin.
Read MoreIron Toxicity Post #26: Red Blood Cell metabolism is by inference Iron metabolism
The objective of iron metabolism is mobilization, and ceruloplasmin is the metabolic agent to guarantee that functional requirement is met.
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